Academic Articles


Articles supported by MBT

Peer-reviewed articles listing MBT as one of the Institutional Affiliations

Ghrelin, Ghrelin O-Acyltransferase, and Carbohydrate Metabolism During Pregnancy in Calorie-Restricted Mice. Trivedi A, Babic S, Heiman M, Gibson WT, Chanoine JP. Horm Metab Res. 2017 Jan;49(1):64-72. Epub 2016 Oct 4.

Antidiabetic Potential of Purple and Red Rice (Oryza sativa L.) Bran Extracts.  Boue SM, Daigle KW, Chen MH, Cao H, Heiman ML. J Agric Food Chem. 2016 Jul 6;64(26):5345-53. Epub 2016 Jun 22.

A healthy gastrointestinal microbiome is dependent on dietary diversity.  Heiman ML, Greenway FL.  Mol Metab. 2016 Mar 5;5(5):317-20. eCollection 2016 May.

A novel gastrointestinal microbiome modulator from soy pods reduces absorption of dietary fat in mice. Boué S, Fortgang I, Levy RJ Jr, Bhatnagar D, Burow M, Fahey G, Heiman ML.Obesity (Silver Spring). 2016 Jan;24(1):87-95. Epub 2015 Nov 20.

Gastrointestinal microbiome modulator improves glucose tolerance in overweight and obese subjects: A randomized controlled pilot trial. Rebello CJ, Burton J, Heiman M, Greenway FL. J Diabetes Complications. 2015 Nov-Dec;29(8):1272-6.  Epub 2015 Sep 3.

Addition of a Gastrointestinal Microbiome Modulator to Metformin Improves Metformin Tolerance and Fasting Glucose Levels. Burton JH, Johnson M, Johnson J, Hsia DS, Greenway FL, Heiman ML. J Diabetes Sci Technol. 2015 Jul;9(4):808-14. Epub 2015 Mar 23.

Acylated ghrelin is not required for the surge in pituitary growth hormone observed in pregnant mice. Trivedi A, Babic S, Heiman M, Gibson WT, Chanoine JP. Peptides. 2015 Mar;65:29-33.. Epub 2015 Jan 30.


Supporting Articles

The fermentable fiber inulin increases postprandial serum short-chain fatty acids and reduces free-fatty acids and ghrelin in healthy subjects. Joshua Tarini, Thomas M.S. Wolever

Effects of high performance inulin supplementation on glycemic control and antioxidant status in women with type 2 diabetes Diabetes Metab J. 2013 Apr;37(2):140-8. Epub 2013 Apr 1

Beta Glucan: Health Benefits in Obesity and Metabolic Syndrome. D El Khoury. Oct , 2011.

Beta-Glucan-enriched bread reduces energy intake and modifies plasma ghrelin and peptide YY concentrations in the short term. P Vitaglione, 2009

Fourteen weeks of treatment with Viscofiber increased fasting levels of glucagon-like peptide-1 and peptide-YY. F. Greenway, 2007.

Six-week consumption of a wild blueberry powder drink increases bifidobacteria in the human gut. S Vendrame, ‎2011. J Agric Food Chem. 2011 Dec 28;59.



Everard A, et al. Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity. Proc Natl Acad Sci U S A. 2013 May 13. [Epub ahead of print]

Fei N, Zhao L. An opportunistic pathogen isolated from the gut of an obese human causes obesity in germfree mice. ISME J. 2013 Apr;7(4):880-4.

Koeth RA, et al. Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis. Nat Med. 2013 May;19(5):576-85.

LeBlanc JG, et al. Bacteria as vitamin suppliers to their host: a gut microbiota perspective. Curr Opin Biotechnol. 2013 Apr;24(2):160-8.

Liou AP, et al. Conserved shifts in the gut microbiota due to gastric bypass reduce host weight and adiposity. Sci Transl Med. 2013 Mar 27;5(178):178ra41

Markle JG, et al. Sex differences in the gut microbiome drive hormone-dependent regulation of autoimmunity. Science. 2013 Mar 1;339(6123):1084-8.

Martinez-Medina M., et al. Western diet induces dysbiosis with increased E coli in CEABAC10 mice, alters host barrier function favouring AIEC colonisation. Gut. 2013 Apr 18. [Epub ahead of print]

Petrof EO, et al. Microbial ecosystems therapeutics: a new paradigm in medicine? Benef Microbes. 2013 Mar 1;4(1):53-65.

Qin J, et al. A metagenome-wide association study of gut microbiota in type 2 diabetes. Nature. 2012 Oct 4;490(7418):55-60.

Stachowicz N, Kiersztan A. The role of gut microbiota in the pathogenesis of obesity and diabetes. Postepy Hig Med Dosw (Online). 2013 Apr 15;67(0):288-303.


Microbiome Special Sections:

Nature. 486, 215–221, June 14, 2012

Science. 336, June 6,  2012


2011 and Older:

Arumugam M, et al. Enterotypes of the human gut microbiome. Nature. 2011;473(7346):174-80.

Blaser MJ. Harnessing the Power of the Human Microbiome. Proc Natl Acad Sci U S A. 2010; 107(14):6125-6.

De Filippo C, et al. Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa. Proc Natl Acad Sci U S A. 2010;107(33):14691-6.

Everard A, et al. Responses of Gut Microbiota and Glucose and Lipid Metabolism to Prebiotics in Genetic Obese and Diet-Induced Leptin-Resistant Mice. Diabetes. 2011 Sep 20. doi: 10.2337/db11-0227.

Goodman AL, et al. Extensive personal human gut microbiota culture collections characterized and manipulated in gnotobiotic mice. Proc Natl Acad Sci U S A. 2011; 108(15):6252-7.

Gordon JI, et al. A rendezvous with our microbes. Proc Natl Adac Sci U S A. 2011;108 Suppl 1:4513-5.

Heijtz RD, et al. Normal gut microbiota modulates brain development and behavior. Proc Natl Acad Sci U S A. 2011; 108(7):3047-52.

Kootte RS, et al. The therapeutic potential of manipulating gut microbiota in obesity and type 2 diabetes mellitus. Diabetes Obes Metab. 2011 Aug 3. doi: 10.1111/j.1463-1326.2011.01483.x.

Ley RE, et al. Obesity alters gut microbial ecology. Proc Natl Acad Sci U S A. 2005; 102(31):11070-5.

Mariat D, et al. The Firmicutes/Bacteroidetes ratio of the human microbiota changes with age. BMC Microbiol. 2009;9:123.

Rooks MG and Garrett WS. Sharing the Bounty. The Scientist. Aug 2011; 25,8:38.

Tsukumo DM, Et al. Translational research into gut microbiota: new horizons in obesity treatment. Arq Bras Endocrinol Metabol. 2009;53(2):139-44.